Kormos, Jennifer Lynne published the artcileBiotransformation of Selected Iodinated X-ray Contrast Media and Characterization of Microbial Transformation Pathways, Formula: C11H9I3N2O4, the main research area is biotransformation iodinated Xray contrast media characterization microbial transformation pathway.
Iodinated x-ray contrast media (ICM) are commonly detected in the aquatic environment at concentrations up to the low μg/L range. The biotransformation of selected ICM (diatrizoate, iohexol, iomeprol, and iopamidol) in aerobic soil-water and river sediment-water batch systems was studied. Microbial transformation pathways are proposed. Diatrizoate, an ionic ICM, was not biotransformed, while 3 nonionic ICM were transformed into several biotransformation products (TPs) at pH 7. Iohexol and iomeprol were biotransformed to 11 and 15 TPs, resp., while 8 TPs were detected for iopamidol. Since seven of the TPs detected during biotransformation had not been previously identified, mass fragmentation experiments were completed to elucidate the chem. structures. Oxidation of primary alc. moieties, cleavage of the N-C bonds (i.e., deacetylation and removal of hydroxylated propanoic acids), and oxidative decarboxylation are potential reactions that can explain the formation of the identified TPs. Iohexol and iomeprol had similar biotransformation rates, while iopamidol was biotransformed slower and to a lesser extent. A LC tandem MS method confirmed the presence of ICM TPs in aqueous environmental samples. Fifteen of the ICM TPs were even detected in drinking water with concentrations â?20 ng/L.
Environmental Science & Technology published new progress about Biodegradation. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Formula: C11H9I3N2O4.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem