With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.347146-33-2,1-Chloroisoquinolin-6-amine,as a common compound, the synthetic route is as follows.
SYNTHETIC EXAMPLE 62b 1-Chloro-6-(4-chlorobenzenesulfonylamino)isoquinoline The title compound was obtained using 6-amino-1-chloro-isoquinoline (Production Example 23b) and 4-chlorobenzenesulfonyl chloride in the same method as in Synthetic Example 1b. 1H-NMR(CDCl3) delta (ppm): 7.33(1H, brs), 7.39(1H, dd, J=2.0, 8.8 Hz), 7.44(2H, d, J=8.8 Hz), 7.50(1H, d, J=5.6 Hz), 7.58(1H, d, J=2.0 Hz), 7.81 (2H, d, J=8.8 Hz), 8.24 (1H, d, J=5.6 Hz), 8.25 (1H, d, J=8.8 Hz). FAB-MS: 353., 347146-33-2
347146-33-2 1-Chloroisoquinolin-6-amine 22674114, aisoquinoline compound, is more and more widely used in various fields.
Reference£º
Patent; Wakabayashi, Toshiaki; Funahashi, Yasuhiro; Hata, Naoko; Semba, Taro; Yamamoto, Yuji; Haneda, Toru; Owa, Takashi; Tsuruoka, Akihiko; Kamata, Junichi; Okabe, Tadashi; Takahashi, Keiko; Nara, Kazumasa; Hamaoka, Shinichi; Ueda, Norihiro; US2004/18192; (2004); A1;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem