Mohammadi, Hadi published the artcileγ-Fe2O3@SiO2-γ-aminobutyric acid as a novel superparamagnetic nanocatalyst promoted green synthesis of chromeno[4,3,2-de][1,6]naphthyridine derivatives, Computed Properties of 86-51-1, the main research area is cascade cyclocondensation malononitrile hydroxyacetophenone aromatic aldehyde chromenonaphthyridine synthesis; superparamagnetic nanocatalyst green synthesis chromenonaphthyridine; iron oxide silica aminobutyric acid superparamagnetic nanocatalyst.
Grafting of γ-aminobutyric acid on the superparamagnetic γ-Fe2O3@SiO2 nanoparticles afforded γ-Fe2O3@SiO2-γ-aminobutyric acid as a novel heterogeneous nanocatalyst, which was characterized by X-ray diffraction, Fourier transform-IR spectroscopy, vibrating sample magnetometry, field emission SEM, energy-dispersive X-ray spectroscopy, and thermal anal. In this research, we report a convenient and one-pot efficient direct protocol for the pseudo four-component preparation of chromeno[4,3,2-de][1,6]naphthyridine derivatives via cascade condensation reaction of malononitrile, 2,4-dihydroxyacetophenone with various aromatic aldehydes in the presence of the catalytic amount of the γ-Fe2O3@SiO2-γ-aminobutyric acid under green conditions in aqueous media [e.g., malononitrile + 2,4-dihydroxyacetophenone + PhCHO â?I (92%)]. This procedure offers several advantages such as: very easy reaction conditions, simple work-up, or purification, excellent yields, high purity of the desired product, atom economy, and short reaction times. The superparamagnetic nanocatalyst is magnetically separable and kept stabile after recycling for at least five consecutive runs without detectable activity loss.
Monatshefte fuer Chemie published new progress about Atom economy. 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Computed Properties of 86-51-1.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem