Navale, Balu S. published the artcilePropargyl α-aryl-α-diazoacetates as robust reagents for the effective C-H bond functionalization of 1,3-diketones via scandium catalysis, Recommanded Product: 4-Methoxyphenylacetic acid, the main research area is propargyl aryl dicarbonyl compound preparation; diketone propargyl aryl diazoacetate alkylation scandium catalyst.
Propargyl α-aryl-α-diazoacetates RC(=N2)C(O)OCH2CCH [R = 4-ClC6H4, naphthalen-2-yl, 3,4-(H3CO)2C6H3, etc.] a new class of reagents is developed for the effective C-H bond functionalization of 1,3-diketones R1C(O)CH2C(O)R1 (R1 = Me, Et, Ph, 4-H3CC6H4, 4-H3COC6H4) at room temperature The combination of scandium triflate and propargyl α-aryl-α-diazoacetates proved to be efficient catalyst-reagent system for the controlled C-H bond functionalization to afford 1,3-dicarbonyl alkylation products RCH(CH(C(O)R1)2)C(O)OCH2CCH. The protocol uses inexpensive Sc(OTf)3 (5 mol%) and the reaction did not require the use of expensive catalysts or ligands and worked efficiently at room temperature The practicality of the protocol has been demonstrated by the gram scale synthesis.
Tetrahedron Letters published new progress about Alkylation. 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Recommanded Product: 4-Methoxyphenylacetic acid.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem