22246-04-4, 7-Methoxy-3,4-dihydroisoquinolin-1(2H)-one is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Step 3: Synthesis of 7-methoxy- 1,2,3, 4-Tetrahydro-isoquinoline; To a slurry of lithium aluminium hydride (2.42 g, 63.56 mmol) in dry tetrahydrofuran at 0 C was added 3,4-dihydro-7-methoxyisoquinolin-l(2H)-one (4.5 g, 25.4 mmol) dissolved in tetrahydrofuran and the solution refluxed for 2 h with stirring. Reaction mixture was quenched at 0 C with water (2.5 mL), 10% sodium hydroxide solution (2.5 mL) and water (7.5 mL). The stirring was continued at room temperature for 30 min. It was filtered through a celite bed which was thoroughly washed with CHCl3 (-100 mL). The CHCl3 was concentrated under reduced pressure to give crude material (2.9 g, 70 %) which was used as such for next step. ESIMS (m/z): 186.0 (M+Na), 164.1 (M+l), 22246-04-4
The synthetic route of 22246-04-4 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; PANACEA BIOTEC LIMITED; WO2009/118765; (2009); A2;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem