6624-49-3, In an article, published in an article,authors is Buerli, Roland W., once mentioned the application of 6624-49-3, Name is Isoquinoline-3-carboxylic acid,molecular formula is C10H7NO2, is a conventional compound. this article was the specific content is as follows.
DNA binding ligands targeting drug-resistant Gram-positive bacteria. Part 1: Internal benzimidazole derivatives
Novel DNA minor-groove binding ligands with a promising antibacterial profile are described. Apart from excellent in vitro potency against multiple Gram-positive bacterial strains such as methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus faecalis (VRE), and penicillin-intermediate Streptococcus pneumoniae (PISP), a small subset of compounds was active against Gram-negative bacteria such as Escherichia coli (E. coli).
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Reference£º
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem