da Silva, Ana C. published the artcileRhodium-catalyzed hydroformylation of allylbenzenes and propenylbenzenes: effect of phosphine and diphosphine ligands on chemo- and regioselectivity, Synthetic Route of 1205-17-0, the main research area is hydroformylation allylbenzene propenylbenzene rhodium phosphine diphosphine; regioselectivity hydroformylation allylbenzene propenylbenzene rhodium ligand effect; chemoselectivity hydroformylation allylbenzene propenylbenzene rhodium ligand effect.
Various allylbenzenes and propenylbenzenes have been hydroformylated with 97-99% chemoselectivity using bis[(μ-acetate)(1,5-cyclooctadiene)rhodium(I)] as catalyst precursor. Regioselectivity of the hydroformylation can be controlled by the nature of phosphorus auxiliary ligands. The Rh-NAPHOS [2,2′-bis[(diphenylphosphino)methyl]-1,1′-binaphthyl] system promotes the hydroformylation of allylbenzenes into linear aldehydes in near 95% selectivity and propenylbenzenes into branched aldehydes with a formyl group in the α-position to the Ph ring in near 90% selectivity, while the Rh-dppp [1,3-bis(diphenylphosphino)propane] system gives branched aldehydes with a formyl group in the β-position in near 70% selectivity starting from allylbenzenes. The regioselectivity of Rh-diphosphine systems correlates with a ligand bite angle. Both the rate and regioselectivity of the hydroformylation are largely influenced by the basicity of monophosphine auxiliary ligands; however, no correlation between their steric characteristics and the regioselectivity has been observed
Journal of Molecular Catalysis A: Chemical published new progress about Chemoselectivity. 1205-17-0 belongs to class isoquinoline, name is 2-Methyl-3-(3,4-methylenedioxyphenyl)propionaldehyde, and the molecular formula is C11H12O3, Synthetic Route of 1205-17-0.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem