Funke, Jan published the artcileOxypurinol – A novel marker for wastewater contamination of the aquatic environment, Safety of Diatrizoic Acid, the main research area is oxypurinol wastewater ground drinking water pollution; Allopurinol; Biological transformation; Drinking water; Groundwater; Rivers.
The anti-gout agent allopurinol is one of the most prescribed pharmaceuticals in Germany and is widely metabolized into oxypurinol (80%) as well as the corresponding riboside conjugates (10%) within the human body. To investigate the occurrence of allopurinol and oxypurinol in the urban water cycle an anal. method was developed based on solid phase extraction (SPE) and subsequent liquid chromatog. electrospray-ionization tandem mass spectrometry (LC-MS/MS).In raw wastewater concentration levels of oxypurinol ranged up to 26.6 μg L-1, whereas allopurinol was not detected at all. In wastewater treatment plant (WWTP) effluents, concentrations of allopurinol were
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem