A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, 486-73-7, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 486-73-7, Name is Isoquinoline-1-carboxylic acid, molecular formula is C10H7NO2. In a Article, authors is Puthongking, Ploenthip£¬once mentioned of 486-73-7
Chemistry of ecteinascidins. Part 2. Preparation of 6?-O-acyl derivatives of stable ecteinascidin and evaluation of cytotoxicity
A large amount of stable ecteinascidin 770 (1b) was isolated from the Thai tunicate, Ecteinascidia thurstoni, which was pretreated with potassium cyanide in buffer solution (pH 7), along with a minor metabolite, ecteinascidin 786 (1c). A number of 6?-O-acyl derivatives 3-19 and three diacetyl derivatives 2a-c of the stable 1b were prepared and evaluated for activity against human tumor cell lines HCT116, QG56, and DU145. Nitrogen-containing heterocyclic ester derivatives such as 12, 13, and 16-19 showed similar in vitro cytotoxicity to 1b, whereas the other derivatives were less cytotoxic than 1b. Furthermore, we discovered that the N-indole-3-carbonyl derivative of ecteinascidin 770 (22) has higher cytotoxicity than 1b.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 486-73-7
Reference£º
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem