Ma, Pengju published the artcilePhotocatalyst- and additive-free decarboxylative alkylation of N-aryl tetrahydroisoquinolines induced by visible light, Formula: C9H10O3, the main research area is alkyl aryl tetrahydroisoquinoline preparation; tetrachlorohydroxyphthalimide alkyl ester aryl tetrahydroisoquinoline decarboxylative alkylation.
Synthesis of C-1 alkylated tetrahydroisoquinoline products I (R = Pr, 4-oxocyclohexyl, oxan-4-yl, etc.; R1 = Ph, pyridin-4-yl, naphthalen-1-yl, etc.; R2 = H. MeO) and II via a visible light induced decarboxylative alkylation of N-aryl tetrahydroisoquinolines III (X = H) and 9-methyl-2-phenyl-1H,2H,3H,4H,9H-pyrido[3,4-b]indole has been developed using tetrachloro-N-hydroxyphthalimide esters IV as alkylation agents. This redox-neutral reaction can proceed without the assistance of photocatalysts, transition metals and external additives by irradiation with blue LEDs. Preliminary mechanistic studies indicated that this transformation probably proceeded through an electron donor-acceptor complex involved radical process.
Organic Chemistry Frontiers published new progress about Alkylation. 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Formula: C9H10O3.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem