Erfkamp, Jan published the artcileEnzyme-functionalized piezoresistive hydrogel biosensors for the detection of urea, Formula: C2H6N2O, the main research area is urea enzyme piezoresistive hydrogel biosensor; alkaline pH conditions; biosensor; hydrogel-based sensor; pH value; piezoresistive pressure sensor; stimuli-responsive hydrogel; urea; urea sensor; urease.
Urea is used in a wide variety of industrial applications such as the production of fertilizers. Furthermore, urea as a metabolic product is an important indicator in biomedical diagnostics. For these applications, reliable urea sensors are essential. In this work, we present a novel hydrogel-based biosensor for the detection of urea. The hydrolysis of urea by the enzyme urease leads to an alk. pH change, which is detected with a pH-sensitive poly(acrylic acid-co-dimethylaminoethyl methacrylate) hydrogel. For this purpose, the enzyme is phys. entrapped during polymerization This enzyme-hydrogel system shows a large sensitivity in the range from 1 mmol/L up to 20 mmol/L urea with a high long-term stability over at least eight weeks. Furthermore, this urea-sensitive hydrogel is highly selective to urea in comparison to similar species like thiourea or N-methylurea. For sensory applications, the swelling pressure of this hydrogel system is transformed via a piezoresistive pressure sensor into a measurable output voltage. In this way, the basic principle of hydrogel-based piezoresistive urea biosensors was demonstrated.
Sensors published new progress about Biosensors. 598-50-5 belongs to class isoquinoline, name is 1-Methylurea, and the molecular formula is C2H6N2O, Formula: C2H6N2O.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem