Yanina, Irina Yu. published the artcileImmersion optical clearing of adipose tissue in rats: ex vivo and in vivo studies, Quality Control of 117-96-4, the main research area is diatrizoic acid dimethylsulfoxide adipose tissue; adipose tissue; diffusion coefficient; ex vivo and in vivo optical clearing; reduced scattering coefficient; refractive index.
Optical clearing (OC) of adipose tissue has not been studied enough, although it can be promising in medical applications, including surgery and cosmetol., for example, to visualize blood vessels or increase the permeability of tissues to laser beams. The main objective of this work is to develop technol. for OC of abdominal adipose tissue in vivo using hyperosmotic optical clearing agents (OCAs). The maximum OC effect (77) was observed for ex vivo rat adipose tissue samples exposed to OCA on fructose basis for 90 min. For in vivo studies, the maximum effect of OC (65) was observed when using OCA based on diatrizoic acid and dimethylsulfoxide for 120 min. Histol. anal. showed that in vivo application of OCAs may induce a limited local necrosis of fat cells. The efficiency of OC correlated with local tissue damage through cell necrosis due to accompanied cell lipolysis.
Journal of Biophotonics published new progress about Adipocyte. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Quality Control of 117-96-4.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem