Nitro-Mannich/lactamization cascades for the direct stereoselective synthesis of pyrrolidin-2-ones was written by Pelletier, Sophie M.-C.;Ray, Peter C.;Dixon, Darren J.. And the article was included in Organic Letters in 2009.Safety of 6,7-Dimethoxy-3,4-dihydroisoquinoline This article mentions the following:
An efficient three-component nitro-Mannich/lactamization cascade of Me 3-nitropropanoate with in situ formed acyclic imines for the direct preparation of pyrrolidinone derivatives has been developed. The reaction is easy to perform, broad in scope, and highly diastereoselective and may be extended to cyclic imines allowing the direct formation of polycyclic pyrrolidinone derivatives In the experiment, the researchers used many compounds, for example, 6,7-Dimethoxy-3,4-dihydroisoquinoline (cas: 3382-18-1Safety of 6,7-Dimethoxy-3,4-dihydroisoquinoline).
6,7-Dimethoxy-3,4-dihydroisoquinoline (cas: 3382-18-1) belongs to isoquinoline derivatives. Quinoline is a mancude organic heterobicyclic parent, an azaarene, an ortho-fused heteroarene and a member of isoquinolines. The discovery of chloroquine, the most well-known drug containing this stent, has helped bring about decades of malaria control and treatment.Safety of 6,7-Dimethoxy-3,4-dihydroisoquinoline
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem