A new application about 6-Methoxy-3,4-dihydroisoquinolin-1(2H)-one

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 22246-12-4, help many people in the next few years.22246-12-4

22246-12-4, Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 22246-12-4, Name is 6-Methoxy-3,4-dihydroisoquinolin-1(2H)-one

Facile synthesis of 5-To 7-membered benzolactam compounds via strongly facilitated electrophilic aromtic substitution reaction

We employed our system to activate aromatic ring-Tethered carbamate compounds with trifluoromethanesulfonic acid to obtain benzolactams with 5-To 7-membered rings, and examined the substrate scope and limitations of this activation method. In 5-membered ring formation, a halogen group on the aromatic ring did not greatly affect the reaction yield, but other electron-donating groups inhibited the cyclization reaction, and various side-reactions occurred. In 7-membered ring formation, eletron-donating groups on aromatic ring promoted the cyclization reaction, but cyclization of electron-deficient aromatic rings did not proceed well. The 6-membered ring formation reaction showed the greatest substrate generality.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 22246-12-4, help many people in the next few years.22246-12-4

Reference£º
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem