Rhodium(III)- and Ruthenium(II)-Catalyzed Olefination of Isoquinolones was written by Zhao, Peng;Niu, Rui;Wang, Fen;Han, Keli;Li, Xingwei. And the article was included in Organic Letters in 2012.Reference of 491-30-5 This article mentions the following:
NH and N-protected isoquinolones undergo Rh(III)-catalyzed oxidative olefination at the 8-position with terminal alkenes to afford alkenylated derivatives, e.g., I (R1 = H, Me, MeO, Cl; R2 = H, n-Pr, n-Bu, SiMe3). Complementary redox-neutral olefination of such isoquinolones using internal alkynes was achieved under ruthenium catalysis. In the experiment, the researchers used many compounds, for example, 1-Hydroxyisoquinoline (cas: 491-30-5Reference of 491-30-5).
1-Hydroxyisoquinoline (cas: 491-30-5) belongs to isoquinoline derivatives. Being an analog of pyridine, isoquinoline is a weak base, with a pKa of 5.14. Isoquinoline-type alkaloids show biological activities similar to those of morphinane-, protoberberine-, and benzophenanthridine-type alkaloids.Reference of 491-30-5
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem