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4494-18-2 1-Isoquinolinecarboxaldehyde 265306, aisoquinoline compound, is more and more widely used in various.

4494-18-2, 1-Isoquinolinecarboxaldehyde is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

During DCE (50mL) 4-(2-aminoethyl) benzenesulfonamide(1.0g, 5.0mmol), AcOH and (1.0 mL) and isoquinoline-1-carbaldehyde(2.09 g, 13.3 mmol) the solution containing the mixture was stirredfor 30 minutes at under 75 C. nitrogen. The reaction mixture was cooled to 0 , and treated with NaBH (OAc) 3 (3.165g,15mmol). The reaction mixture was stirred at room temperature overnight anddecomposed with water. The reaction mixture was extracted with DCM.The organic layer was dried and concentrated in vacuo.The residue was purified by flash chromatography on silica gel to yield 4- (2-(bis (isoquinolin-1-ylmethyl) amino) ethyl) benzenesulfonamide (1.86 g, 77%).

4494-18-2 1-Isoquinolinecarboxaldehyde 265306, aisoquinoline compound, is more and more widely used in various.

Reference£º
Patent; MOLECULAR INSIGHT PHARMACEUTICALS INCORPORATED; BABICH, JOHN W; (133 pag.)JP5856247; (2016); B2;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem