58794-09-5, 7-Bromoisoquinoline is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A cold solution of tert-butyl (1 -oxoisoquinolin-2(1 -/)-yl)acetate (1.2 g, 4.6mmol) in dichloromethane (20 mL) was treated with trifluoroacetic acid (10 mL) dropwise. The reaction mixture was then stirred at room temperature for 3h. The solvent was evaporated and the residue was azeotroped with toluene. The solid formed was triturated with ether to afford the title compound. 1 H NMR (400 MHz, DMSO-d6): delta 10.76 (s, 1 H), 8.18-8.20 (m, 1 H), 7.64-7.73 (m, 2H), 7.42- 7.52 (m, 2H), 6.62 (d, J= 8.0 Hz, 1 H), 4.67 (s, 2H). MS (ESI+): 204.3, HPLC (Method A) Rt 2.34 min; HPLC purity 99.3 %
As the paragraph descriping shows that 58794-09-5 is playing an increasingly important role.
Reference£º
Patent; ARES TRADING S.A.; SWINNEN, Dominique; MORANDI, Federica; WO2013/92979; (2013); A1;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem