19493-45-9, 3-Chloroisoquinoline is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Method AA Step 1 A mixture of F6 (20.0 mg, 0.049 mmol), Cul (3.7 mg, 0.019 mmol), 3- chloroisoquinoline (16.1 mg, 0.098 mmol), N,N-dimethylglycine (4.1 mg, 0.039 mmol) and Cs2C03 (35.2 mg, 0.108 mmol) in dioxane (3 mL) was stirred at 100 C for 14 h. The reaction mixture was quenched with water and extracted with EtOAc (15 mL x 4). The combined extracts were washed with brine (10 mL), dried over Na2S04, filtered and the filtrate was concentrated in vacuo. The residue was purified by p-HPLC (TFA condition) to give Example 77.
19493-45-9 3-Chloroisoquinoline 640968, aisoquinoline compound, is more and more widely used in various.
Reference£º
Patent; MERCK SHARP & DOHME CORP.; DAI, Xing; CUMMING, Jared, N.; LIU, Hong; SCOTT, Jack, D.; (0 pag.)WO2016/85780; (2016); A1;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem