7651-81-2, Isoquinolin-3(2H)-one is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
In a sealed reaction vessel, a stirred mixture of 3-hydroxyisoquinoline (500 mg, 3.44 mmol) and ethyl methacrylate (1.29 mL, 10.3 mmol) in toluene (10 mL) was heated to 170 C. where it stirred for 16 h. After this time, the reaction mixture was concentrated to yield crude product. The crude product was purified by preparative HPLC to provide a fraction containing isomers A and B in a 3:1 ratio (A:B) as an oil (284 mg, 32% yield). MS (E+) m/z: 260 (MH+); LC retention time (Method A): 2.41 min (broad). A second fraction containing isomers C and D in a 5:1 ratio (C:D) was obtained as a solid (502 mg, 56%). MS (E+) m/z: 260 (MH+); LC retention time (Method A): 2.70 min (broad).
As the paragraph descriping shows that 7651-81-2 is playing an increasingly important role.
Reference£º
Patent; Weinstein, David S.; Gilmore, John L.; Sheppeck, James; Yang, Bingwei Vera; Kim, Soong-Hoon; Vaccaro, Wayne; US2005/187242; (2005); A1;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem