23687-25-4, Isoquinolin-4-amine is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,23687-25-4
In a single-necked round-bottomed flask isoquinoline-4-amine (1 .50 g, 10.4 mmol) and 4-methoxybenzenesulfonyl chloride (2.47 g, 1 1.96 mmol) were dissolved in anhydrous pyridine (18 ml.) and stirred at room temperature overnight. Upon completion of the reaction determined by TLC, the reaction was diluted with water (50 ml.) and extracted with EtOAc (25 ml_). The layers were separated, and the aqueous layer was extracted with EtOAc (2 c 25 ml_). The combined organics were washed with water (50 ml_), brine (2 c 50 ml_), dried over Na2S04, and concentrated under reduced pressure to a brown oil. Toluene (50 ml.) was added to the oil and removed under reduced pressure to yield an orange solid. The crude product was purified by recrystallization from toluene to yield 2.50 grams (77% yield) of (13) as an orange solid.
The synthetic route of 23687-25-4 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS; MOORE, Terry; LAZZARA, Phillip; DAVID, Brian; RICHARDSON, Benjamin; JAIN, Atul, D.; (87 pag.)WO2019/195348; (2019); A1;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem