With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.131002-09-0,6-Chloroisoquinolin-1(2H)-one,as a common compound, the synthetic route is as follows.
6-chloroisoquinolin-1 (2Eta)-one (12 mmol), diphenyl disulfide (10 mmol), silver hexafluoroantimonate (12 mmol) and 6 parts were sequentially added to a pressure-resistant reaction tube at room temperature. Dichloroethane (6 mL). The reaction mixture was then reacted at 100 C for 8 hours. The reaction was stopped, concentrated under reduced pressure to give a crude material, which was washed with a mixture of petroleum ether and ethyl acetate. 4-phenylthio-6-chloroisoquinolin-1 (2H)-one. Yield 80%;, 131002-09-0
131002-09-0 6-Chloroisoquinolin-1(2H)-one 21779697, aisoquinoline compound, is more and more widely used in various.
Reference£º
Patent; Nankai University; Zhu Youquan; He Jingli; Niu Yunxia; Han Tingfeng; Li Haoyu; (14 pag.)CN108822035; (2018); A;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem