Downstream synthetic route of 23687-26-5

23687-26-5, The synthetic route of 23687-26-5 has been constantly updated, and we look forward to future research findings.

23687-26-5, 6-Aminoisoquinoline is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

EXAMPLE 87 Preparation of benzylisoquinolin-6-ylcarbamate (E87) To 6-aminoisoquinoline in DMF at -40¡ã C. was added NaH and solution was warmed to 0¡ã C. for 30 minutes. Then benzylchloroformate was added and the reaction stirred at 0¡ã C. for 2 hours. The solution was quenched with AcOH, poured into NaHCO3(sat) and extracted with EtOAc, dried (Na2SO4), filtered and evaporated. Flash chromatography (SiO2 90percent EtOAc/Hex) gave benzylisoquinolin-6-ylcarbamate. (E87).

23687-26-5, The synthetic route of 23687-26-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; AERIE PHARMACEUTICALS, INC.; US2008/167340; (2008); A1;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem