34784-05-9, 6-Bromoisoquinoline is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
a) 6-( 1 -piperazinyl)isoquinoline6-Bromoisoquinoline (333 mg, 1.60 1 mmol) and palladium(II) acetate (17.97 mg,0.080 mmol) were placed in a microwave vial followed by piperazine (827 mg, 9.60 mmol), sodium tert-butoxide (215 mg, 2.24 1 mmol), and p-xylene (10 mL). The vial was capped andflushed with nitrogen and tris(1,1-dimethylethyl)phosphane (1M solution in toluene, 80 uL,0.080 mmol) was injected into the vial via syringe. The reaction was stirred and heated to 120C for 1 h. The xylene was evaporated under reduced pressure and the crude product wastaken up in dichloromethane and washed with water (2x). The organic layer was filtered toremove the catalyst, dried with sodium sulfate, and evaporated under reduced pressure toafford the title product (300 mg, 88%), which was used without further purification.MS(ES)+ mle 214.2 [M+H].
34784-05-9, 34784-05-9 6-Bromoisoquinoline 313681, aisoquinoline compound, is more and more widely used in various fields.
Reference£º
Patent; GLAXOSMITHKLINE LLC; ADAMS, Nicholas, David; KIESOW, Terence, John; WIGGALL, Kenneth; WO2013/177253; (2013); A2;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem