With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.347146-33-2,1-Chloroisoquinolin-6-amine,as a common compound, the synthetic route is as follows.
Synthetic Example 61b 1-Chloro-6-(4-cyanobenzenesulfonylamino)isoquinoline The title compound was obtained using 6-amino-1-chloro-isoquinoline (Production Example 23b) and 4-cyanobenzenesulfonyl chloride in the same method as in Synthetic Example 1b. 1H-NMR(DMSO-d6) delta (ppm): 7.52(1H,dd,J=2.0,8.8Hz), 7.68(1H, d,J=2.0Hz), 7.79(1H,d,J=5.6Hz), 8.03(4H,m), 8.18(1H,d,J=5.6Hz), 8.21(1H,d,J=8.8Hz), 11.36(1H,s)., 347146-33-2
The synthetic route of 347146-33-2 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Eisai Co., Ltd.; EP1258252; (2002); A1;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem