With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.23687-25-4,Isoquinolin-4-amine,as a common compound, the synthetic route is as follows.
Example 17 N-(1-Methyl-5-indolyl)-N’-(4-isoquinolyl) urea (E17) The title compound was prepared from 4-aminoisoquinoline, 1,1′-carbonyl diimidazole and 5-amino-1-methyl-indole using a procedure similar to that described for Example 1, and then converted to the hydrochloride salt using hydrogen chloride in ether/ethanol, in 26% overall yield, m.p. 195-197 C., 23687-25-4
The synthetic route of 23687-25-4 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; SmithKline Beecham, p.l.c.; US5508288; (1996); A;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem