Analyzing the synthesis route of 164148-92-9

164148-92-9, As the paragraph descriping shows that 164148-92-9 is playing an increasingly important role.

164148-92-9, tert-Butyl 6-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a stined 0 C solution of tert-butyl 6-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate (1 g, 4.02 mmol) in DCM (15 mL) was added Et3N (1.7 mL, 12.07 mmol) followed by (CF3CO)20 (0.85 mL, 6.03 mmol). The ice bath was removed, and the reaction was stined at RT for 2 h. After completion of the reaction, the reaction was diluted with DCM (20 mL) washed with sat. NaHCO3 (2 x 20 mL), water (20 mL) and brine (20 mL), dried (Na2504) and evaporated under vacuum to afford tert-butyl 6-(2,2,2- trifluoroacetamido)-3,4-dihydro isoquinoline-2(1H)-carboxylate (1.2 g, 81%) as a brown solid; MS (ESI) mlz 289.4 [(M-tBu)+H].

164148-92-9, As the paragraph descriping shows that 164148-92-9 is playing an increasingly important role.

Reference£º
Patent; ZENO ROYALTIES & MILESTONES, LLC; HUANG, Peter, Qinhua; BOREN, Brant, Clayton; BUNKER, Kevin, Duane; LIU, Hui; PALIWAL, Sunil; (99 pag.)WO2019/28008; (2019); A1;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem