With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1196-38-9,3,4-Dihydroisoquinolin-1(2H)-one,as a common compound, the synthetic route is as follows.
Potassium nitrate (3.71 g, 36.7 mmol) was added to concentrated sulfuric acid (27 mL).3,4-Dihydroisoquinoline-1(2H)-one (4.50 g, 30.6 mmol) was added at 0 C for 2 hours.The reaction solution was poured into ice water, suction filtered, and the obtained solid was washed with water and dried.The title compound (4.00 g, yield 68.0%) was obtained.
1196-38-9, The synthetic route of 1196-38-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Shandong Xuanzhu Pharmaceutical Technology Co., Ltd.; Wang Tingzhong; Chen Bo; Zhu Peng; Liu Bin; (66 pag.)CN110294742; (2019); A;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem