679433-91-1, 5-Bromo-8-methoxyisoquinoline is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,679433-91-1
To a mixture of l-bromo-5-methoxynaphthalene1 (320 mg, 1.3 mmol) and 4-aminophenylboronic acid (HCl salt, 320 mg, 1.85 mmol) in dioxane (3 mL)-H20 (3 mL) was added PdCl2(dppf)-dichloromethane (53 mg, 0.063 mmol) and Na2CO3 (530 mg, 4.2 mmol). The mixture was heated to 1000C for 12 h and cooled to room temperature. The mixture was extracted with dichloromethane and the organic phase was dried over Na2SO^ concentrated, and purified on silica with 5% (2N NH3 in MeOH) in dichloromethane to afford the product as a tan solid (300 mg, 89%). MS (ESI pos. ion) m/z: 251 (M+H).
As the paragraph descriping shows that 679433-91-1 is playing an increasingly important role.
Reference£º
Patent; AMGEN INC.; WO2007/5668; (2007); A2;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem