With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.63927-23-1,5-Bromo-8-nitroisoquinoline,as a common compound, the synthetic route is as follows.
63927-23-1, 3. Synthesis of 5-bromo-8-nitro-iv~-methylisoquinolinium iodide.Iodomethane (506 mmol) was added to a solution of 5-bromo-8-nitroisoquinoline (101 mmol) in N,iV-dimethylformamide (200 mL) and the reaction mixture was maintained for 16 h at 40 0C. The precipitated solids were collected by filtration, washed with ether (2 x 250 mL), and dried to provide 5-bromo-8-nitro-7V-methylisoquinolinium iodide in 83% yield as a red solid.
63927-23-1 5-Bromo-8-nitroisoquinoline 816983, aisoquinoline compound, is more and more widely used in various fields.
Reference£º
Patent; MEMORY PHARMACEUTICALS CORPORATION; DANCA, Mihaela, Diana; DUNN, Robert; TEHIM, Ashok; XIE, Wenge; WO2010/21797; (2010); A1;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem