486-73-7, Isoquinoline-1-carboxylic acid is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
1-Hydroxybenzotriazole hydrate (1.47 equiv of acid), N-ethyl-N’-(3-dimethylaminopropyl)carbodiimide hydrochloride (1.47 equiv of acid), N,N-diisopropylethylamine (3.45 equiv of acid), and corresponding acid were added to a solution of compound 10 (1.0 equiv of acid) in dichloromethane (0.1 M). The reaction mixture was stirred at room temperature for 12 h and then washed with water. The separated organic layer was dried over anhydrous sodium sulfate and then concentrated under reduced pressure. The concentrate was purified with silica gel column chromatography to afford compound 11., 486-73-7
The synthetic route of 486-73-7 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Lee, Seung Kyu; Choi, Kwang Hyun; Lee, Sang Jae; Lee, Jong Sun; Park, Ji Yun; Kim, B. Moon; Lee, Bong Jin; Bioorganic and Medicinal Chemistry Letters; vol. 21; 1; (2011); p. 133 – 136;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem