Brief introduction of 3-Methylisoquinoline

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Reference of 1125-80-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.1125-80-0, Name is 3-Methylisoquinoline, molecular formula is C10H9N. In a Article£¬once mentioned of 1125-80-0

Alkylation of quinoline and isoquinoline in the presence of LiCl

The in situ generated EEDQ and EEDI reacted with alkylating reagents such as diethyl malonate, ethyl acetoacetate etc. in the presence of a 0.5 equiv of LiCl in acetonitrile to provide the corresponding products in high yields. EEDQ and EEDI generated in situ by the reaction of quinoline and isoquinoline with diethyl pyrocarbonate was treated with alkylating reagents having an activated carbon such as diethyl malonate, ethyl acetoacetate etc. in the presence of 0.5 equiv of LiCl in acetonitrile to provide the corresponding alkyl dihydroquinolines and alkyl dihydroisoquinolines in high yields.

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Reference£º
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem