Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Recommanded Product: 22246-12-4. Introducing a new discovery about 22246-12-4, Name is 6-Methoxy-3,4-dihydroisoquinolin-1(2H)-one
2-(Pyrrolidin-1-yl)ethyl-3,4-dihydroisoquinolin-1(2H)-one derivatives as potent and selective histamine-3 receptor antagonists
On the basis of the previously reported benzimidazole 1,3?- bipyrrolidine benzamides (1), a new class of 2-(pyrrolidin-1-yl)ethyl-3,4- dihydroisoquinolin-1(2H)-one derivatives (3-50) were synthesized and evaluated as potent H3 receptor antagonists. In particular, compound 39 exhibited potent in vitro binding and functional activities at the H3 receptor, good selectivities against other neurotransmitter receptors and ion channels, acceptable pharmacokinetic properties, and a favorable in vivo profile.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Recommanded Product: 22246-12-4, you can also check out more blogs about22246-12-4
Reference£º
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem