19493-44-8, Name is 1-Chloroisoquinoline, belongs to isoquinoline compound, is a common compound. Computed Properties of C9H6ClNIn an article, once mentioned the new application about 19493-44-8.
Studies on the coupling of substituted 2-amino-1,3-oxazoles with chloro-heterocycles
Direct coupling of five-membered heterocyclic amines with halo-heterocycles is a notoriously recalcitrant transformation. Herein we report our findings on the coupling of substituted 2-amino-1,3-oxazoles with chloro-heterocycles. Whereas the coupling of 2-amino-1,3-oxazole is inefficient under a large variety of state-of-the-art catalytic conditions tested, coupling of an ester substituted 2-amino-1,3-oxazole is relatively efficient and provides access, via a hydrolysis-decarboxylation protocol, to the 2-amino-1,3-oxazole coupled products.
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Reference£º
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem