One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, SDS of cas: 486-73-7, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 486-73-7, Name is Isoquinoline-1-carboxylic acid, molecular formula is C10H7NO2
Synthesis and study of substituted amides of isoquinoline-3- and isoquinoline-1-carboxylic acids as potential anticonvulsants
Previously obtained benzylamides of isoquinoline-3-carboxylic acids and isoquinoline-1-carboxylic acids exhibited anticonvulsant activity. In search for more effective anticonvulsants, a series of amides of isoquinoline-3- and isoquinoline-1-carboxylic acids have been synthesized (1-9). The obtained compounds were evaluated qualitatively for their anticonvulsant activity in the maximal electroshock seizure test (MES test), minimal clonic seizure test (6Hz test) and subcutaneous metrazol seizure threshold test (sc MET test) as well as in the rotorod neurotoxicity test (Tox test). One selected compound was tested quantitatively in 6Hz-test in mice after intraperitoneal administration and showed activity ED50 = 385.69 mg/kg and TD50 > 600 mg/kg (1).
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. SDS of cas: 486-73-7, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 486-73-7, in my other articles.
Reference£º
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem