Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. HPLC of Formula: C10H5BrN2. Introducing a new discovery about 27224-09-5, Name is 4-Bromoisoquinoline-1-carbonitrile
Design of Nonpeptidal Ligands for a Peptide Receptor: Cholecystokinin Antagonists
A series of 3-substituted-5-phenyl-1,4-benzodiazepines, nonpeptidal antagonists of the peptide hormone cholecystokinin (CCK), have been synthesized.Designed on the basis of facts regarding CCK, its natural-product antagonist asperlicin (3), and the antianxiety agent diazepam (4), these compounds represent a significant departure from existing CCK antagonists.They also constitute perhaps the first examples of simple, nonpeptidal ligands for a peptide receptor to arise by design rather than by screening.These compounds serve to illuminate the distinction between central and peripheral CCK receptors, as well as to provide orally effective CCK antagonists of potential pharmacological or therapeutic utility.One rationale for their receptor affinity has possible applications in the design of nonpeptidal ligands for other receptors, peptidal as well as nonpeptidal.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.HPLC of Formula: C10H5BrN2, you can also check out more blogs about27224-09-5
Reference£º
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem