Electric Literature of 1532-72-5, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.1532-72-5, Name is Isoquinoline N-Oxide, molecular formula is C9H7NO. In a Article£¬once mentioned of 1532-72-5
Regioselective decarboxylative cross-coupling of carboxy isoquinoline N -oxides
A straightforward method for direct decarboxylative arylation of 1- and 3-carboxy isoquinaldic acid N-oxides with aryl iodides is reported. The reaction proceeded selectively at the carboxy function site to exclusively give the corresponding C-1 or C-3 arylated product. This methodology tolerates various aryl iodides substituted by electronically different groups. Combined with subsequent Reissert-Henze chlorination and SNAr amination, the decarboxylative arylation provides an efficient access to 1,3-functionalized isoquinoline-based antitumor agent.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 1532-72-5, and how the biochemistry of the body works.Electric Literature of 1532-72-5
Reference£º
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem