4602-73-7, Name is 7-Hydroxy-6-methoxy-3,4-dihydroisoquinoline, belongs to isoquinoline compound, is a common compound. Product Details of 4602-73-7In an article, once mentioned the new application about 4602-73-7.
Regio- and Stereoselective Synthesis of Spirooxindoles via Mizoroki-Heck Coupling of Aryl Iodides
A method for highly regio- and stereoselective intramolecular Mizoroki-Heck 5- exo cyclization of aryl iodides to the corresponding spirooxindoles has been developed. Electron-rich and electron-deficient aryl iodide precursors were selectively ring-closed with high stereoselectivity and good yields. The double-bond position in the cyclopentene ring was controlled by careful choice of reaction conditions. These rare spiro compounds were further functionalized to rigidified unnatural amino acid derivatives by a subsequent gas-free Pd(0)-catalyzed alkoxycarbonylation, followed by selective O – and N -deprotections.
Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 4602-73-7
Reference£º
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem