Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Wang, Huanhuan, once mentioned the application of 521284-21-9, Name is (R)-2-((4-Nitrophenethyl)amino)-1-phenylethanol hydrochloride, molecular formula is C16H19ClN2O3, molecular weight is 322.79, MDL number is MFCD26407510, category is isoquinoline. Now introduce a scientific discovery about this category, Formula: C16H19ClN2O3.
Generation of diverse isoquinoline N-oxides in an aqueous system
4-Halo isoquinoline N-oxides could be synthesized efficiently via the electrophilic cyclization of 2-alkynylbenzaldoximes, involving the in situ generation of the halonium ion in water. The one-pot cyclization-Suzuki reaction in an aqueous system afforded the functionalized isoquinoline N-oxides in good yields.
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Reference:
Isoquinoline – Wikipedia,
,Isoquinoline | C9H7N – PubChem