Electric Literature of 36476-78-5, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 36476-78-5, Name is Azetidine-3-carboxylic acid, SMILES is O=C(C1CNC1)O, belongs to isoquinoline compound. In a article, author is Yamashita, Shuji, introduce new discover of the category.
Efficient and stereoselective installation of isoquinoline: formal total synthesis of cortistatin A
The highly stereoselective attachment of isoquinoline onto the steroidal framework of cortistatin A has been achieved. Our strategy features a Ce-mediated nucleophilic addition of an isoquinoline unit to the sterically congested ketone followed by formation of the phenyl thiocarbamate, and Subsequent stereoselective radical reduction. The new method results in a formal total synthesis of cortistatin A. (C) 2009 Elsevier Ltd. All rights reserved.
Electric Literature of 36476-78-5, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 36476-78-5 is helpful to your research.
Reference:
Isoquinoline – Wikipedia,
,Isoquinoline | C9H7N – PubChem