Final Thoughts on Chemistry for 214045-84-8

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Reference of 214045-84-8, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 214045-84-8, Name is 6-Fluoro-3,4-dihydroisoquinolin-1(2H)-one,introducing its new discovery.

NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND BENAMIDE COMPOUNDS AND DRUGS CONTAINING THE SAME

Disclosed are compounds represented by formula (I) which have triglyceride biosynthesis inhibitory activity in the liver and inhibitory activity against the secretion of apolipoprotein B-containing lipoprotein from the liver and particularly have excellent inhibitory activity against the secretion of apolipoprotein B-containing lipoprotein, are free from side effect of accumulation of lipids in the liver, and are useful for the treatment and prevention of hyperlipidemia and arteriosclerotic diseases. In formula (I), R1and R2represent alkyl, alkoxy, cycloalkyl, phenyl, alkenyl, alkynyl, or a five- or six-membered saturated or unsaturated heterocyclic ring, or R1and R2, together with a nitrogen atom to which R1and R2are attached, may form a ring; R3and R4represent a hydrogen atom, alkyl, a halogen atom, hydroxyl, nitrile, alkoxycarbonyl, alkoxy, or carboxyl; or R2and R3may be attached to each other to form -(CH2)m-, -N=CH-, -CH=N-, or -(C1-6alkyl)C=N-; A, D, E, and G each represent a carbon atom, or any one of A, D, E, and G represents a nitrogen atom with the other three each representing a carbon atom; Q represents a nitrogen atom or a carbon atom; Y represents a group represented by formula (II) wherein X represents a hydrogen atom, group -C(=O)N(R5)R6or group -C(=O)OR7, R8is absent or represents a bond, an oxygen atom, a sulfur atom, -SO2-, -SO-, -CH2-CH2-, or – CH=CH-, and R9and R10represent a hydrogen atom, alkyl, alkoxy, a halogen atom, or hydroxyl; and Z represents – (CH2)n-, -O-(CH2)i-, or -C(=O)NH-(CH2)i-.

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Reference£º
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem