New explortion of 1-Methoxyisoquinolin-3-amine

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Related Products of 80900-33-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.80900-33-0, Name is 1-Methoxyisoquinolin-3-amine, molecular formula is C10H10N2O. In a Article，once mentioned of 80900-33-0

A Synthesis of Benzo<1,8>naphthyridinones: an Exception to the Knorr Reaction

The reaction of 1-methoxyisoquinolin-3-amine with ethyl acetoacetate, and subsequent ring closure, is reported.Conrad-Limpach synthesis leads to the expected 4(1H)-one.The same isomer is formed under Knorr conditions (hot polyphosphoric acid), while a less acidic medium (hot acetic acid) gives the 2(1H)-one.

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Reference：
Isoquinoline – Wikipedia,
Isoquinoline | C9H1984N – PubChem