Brief introduction of 22246-12-4

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, COA of Formula: C10H11NO2, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 22246-12-4

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, COA of Formula: C10H11NO2, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 22246-12-4, Name is 6-Methoxy-3,4-dihydroisoquinolin-1(2H)-one, molecular formula is C10H11NO2

We report herein the design, synthesis, and structure-activity relationship studies of conformationally restricted mutilin 14-carbamates based on the structure of SB-222734. The antibacterial activities of these newly synthesized compounds were also evaluated and compared with linezolid and retapamulin. Results showed that most of the target compounds exhibit good potency in inhibiting the growth of Gram-positive bacteria including Methicillin- susceptible Staphylococcus aureus MSSA (MIC: 0.0625-2 mug/mL), Methicillin-resistant S. aureus MRSA (MIC: 0.0625-2 mug/mL), Methicillin-susceptible Staphylococcus epidermidis MSSE (MIC: 0.0625-2 mug/mL), Methicillin-resistant S. epidermidis MRSE (MIC: 0.0625-2 mug/mL), and Streptococcus pneumonia (MIC: 0.0625-4 mug/mL). In particular, three remarkable compounds of this series (12l, 12m, and 21l) exhibited comparable in vitro antibacterial profiles to that of retapamulin.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, COA of Formula: C10H11NO2, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 22246-12-4

Reference：
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem