Awesome and Easy Science Experiments about 1125-80-0

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1125-80-0, Name is 3-Methylisoquinoline, belongs to isoquinoline compound, is a common compound. Application In Synthesis of 3-MethylisoquinolineIn an article, once mentioned the new application about 1125-80-0.

(Chemical Equation Presented) Inexpensive aromatic feedstocks are substrates for highly enantioselective acylative Mannich reactions catalyzed by a thiourea chiral hydrogen-bond donor 1. This methodology provides access to useful 1-substituted dihydroisoquinolines (see scheme; TrocCl = 2,2,2-trichloroethyl chloroformate, TBS = tert-butyldimethylsilyl), which serve as precursors to enantioenriched 1-substituted tetrahydroisoquinolines.

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Reference:
Isoquinoline – Wikipedia,
Isoquinoline | C9H152N – PubChem