Archives for Chemistry Experiments of 55270-33-2

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55270-33-2, Name is 4-Iodoisoquinoline, belongs to isoquinoline compound, is a common compound. category: IsoquinolinesIn an article, once mentioned the new application about 55270-33-2.

Stille coupling under standard conditions proceeds in low yield when using hindered organostannanes (1) or (2) and aryl bromide partners. The inclusion of aryl iodide instead of aryl bromide with the same organostannanes, significantly improves the efficiency of the coupling, providing a variety of desired products in good to excellent yield. The yields of Stille coupling are compared to the different reactivity of aryl halides. This study of Stille coupling with different aryl halides are documented and rationalized.

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Reference:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem