Related Products of 80278-67-7, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.80278-67-7, Name is Isoquinoline-5-carbaldehyde, molecular formula is C10H7NO. In a Article，once mentioned of 80278-67-7
A series of bis-(arylmethylidene)-cycloalkanones was synthesized by cross-aldol condensation. The activity of the compounds was evaluated against amastigotes forms of Trypanosoma cruzi and promastigotes forms of Leishmania amazonensis. The cytotoxicity of the active compounds on uninfected fibroblasts or macrophages was established in vitro to evaluate the selectivity of their antiparasitic effects. Six compounds displayed trypanocidal activity against amastigotes intracellular forms of T. cruzi with IC50 values ranging from 7.0 to 249 muM. Besides these six compounds, eight other molecules exhibited significant leishmanicidal activity (IC50 values ranging from 0.6 to 110.4 muM). Two compounds can be considered as promising antiparasitic lead molecules because they showed IC50 values in the low-micromolar range (?1.2 muM) with an adequate SI (?19.9). To understand the mechanism of action of these compounds, two possible molecular targets were investigated: trypanothione reductase (TR) and cruzain.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 80278-67-7
Reference：
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem