Related Products of 34784-05-9, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.34784-05-9, Name is 6-Bromoisoquinoline, molecular formula is C9H6BrN. In a Patent，once mentioned of 34784-05-9
The invention relates to a 2 – methyl – 1 – oxo – 1, 2 – ISO-quinoline – 6 – carboxylic acid synthesis method, is to 6 – bromine different quinoline as raw materials, adding meta-chloroperoxybenzoic acid, the reaction overnight under the room temperature condition, after the reaction is complete the mixture obtained from 6 – bromine different quinoline nitrogen oxides, to be added to the phosphorus oxychloride in batches, temperature reaction, cooling to separate out a large quantity of solid, cleaning and drying to obtain 6 – bromo – 1 – chloroisonicotinic quinoline, aqueous phase extraction, the organic phase directly turns on lathe does, reach the purity is greater than 95% of the 6 – bromo – 1 – chloroisonicotinic quinoline, the 6 – bromo – 1 – chloroisonicotinic quinoline put in the THF, adding n-BuLi and carbon dioxide gas, to obtain 1 – chloroisonicotinic quinoline – 6 – carboxylic acid, is added to the concentrated hydrochloric acid, to obtain white solid 1 – oxo – 1, 2 – ISO-quinoline – 6 – carboxylic acid, the 1 – oxo – 1, 2 – ISO-quinoline – 6 – is put into the solvent in formic acid, add carbonate cesium and drop Iodized methane, to obtain 2 – methyl – 1 – oxo – 1, 2 – ISO-quinoline – 6 – carboxylic acid methyl ester, the 2 – methyl – 1 – oxo – 1, 2 – ISO-quinoline – 6 – carboxylic acid methyl ester is added to the in methanol, added to the NaOH solution, the decompression steams methanol, adjusting PH=2, separating solid and filtering, cleaning and drying to obtain 2 – methyl – 1 – oxo – 1, 2 – ISO-quinoline – 6 – carboxylic acid. The method route is rational, less waste, higher yield, raw material saving and easy operation. (by machine translation)
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 34784-05-9, and how the biochemistry of the body works.Related Products of 34784-05-9
Reference：
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem