The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: Diphenyl-2-pyridylphosphine(SMILESS: P(C1=CC=CC=C1)(C2=CC=CC=C2)C3=NC=CC=C3,cas:37943-90-1) is researched.Electric Literature of C15H11NO. The article 《The alkoxycarbonylation of protected propargyl alcohols》 in relation to this compound, is published in Molecular Catalysis. Let’s take a look at the latest research on this compound (cas:37943-90-1).
Palladium-catalyzed alkoxycarbonylation of the C≡C triple bond of propargyl alc. was a sustainable synthetic approach to 2-(hydroxymethyl)acrylates I [R = Me, Et, n-Pr, i-Pr; R1 = Ac, Bn], a family of valuable intermediates. The developed synthetic protocol included protection of the alc. function of the alkyne before its carbonylation in the presence of Drent’s catalytic system. Protection step effectively extended the catalyst life hence enhancing the practical applicability of the reaction. The effectiveness of some different protecting groups (benzyl, acetyl and trimethylsilyl) was assessed and the influence of the reaction parameters investigated.
As far as I know, this compound(37943-90-1)Reference of Diphenyl-2-pyridylphosphine can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem