In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Synthesis and anticancer activity evaluation of 3-(4-oxo-2-thioxothiazolidin-5-yl)-1H-indole-carboxylic acids derivatives, published in 2020, which mentions a compound: 67929-86-6, mainly applied to oxo thioxothiazolidinyl indole carboxylic acid preparation antitumor activity, Safety of Methyl 5-methoxyindole-2-carboxylate.
A mild and efficient method for the synthesis of 1-oxo-9H-thiopyrano[3,4-b]indole-3-carboxylic acids I (R = F, H, OMe) and dimerized 3-(4-carboxy-1H-3-indolyl)-2-propenoic acids II (R1 = Me, Et) via alk. hydrolysis of 3-(rhodanin-5-yl)-1H-indole-2-carboxylic acids derivatives III (R2 = H, methoxycarbonyl; R3 = H, methoxycarbonyl, carboxy; R4 = H, Me, Et) was elaborated. Anticancer activity screening in NCI60-cell lines assay allowed identification of III (R = F; R2 = R4 = H; R3 = methoxycarbonyl) with significant antimitotic activity at micromolar and submicromolar concentrations
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Reference:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem