Synthetic Route of C17H14NP. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: Diphenyl-2-pyridylphosphine, is researched, Molecular C17H14NP, CAS is 37943-90-1, about Zinc/Indium Bimetallic Lewis Acid Relay Catalysis for Dehydrogenative Silylation/Hydrosilylation Reaction of Terminal Alkynes with Bis(hydrosilane)s. Author is Tani, Tomohiro; Sohma, Yudai; Tsuchimoto, Teruhisa.
When mixed with two different Lewis acid catalysts of Zn and In, terminal alkynes react with bis(hydrosilane)s to selectively provide 1,1-disilylalkenes from among several possible products, by way of a sequential dehydrogenative silylation/intramol. hydrosilylation reaction. Adding a pyridine base is crucial in this reaction; a switch as a catalyst of the Zn Lewis acid is turned on by forming a Zn-pyridine-base complex. A range of the 1,1-disilylalkenes can be obtained by a combination of aryl and aliphatic terminal alkynes plus aryl-, heteroaryl-, and naphthyl-tethered bis(hydrosilane)s. The 1,1-disilylalkene prepared here is available as a reagent for further transformations by using its C-Si or C:C bond. The former includes Hiyama cross-coupling, Bi-catalyzed ether formation, and iododesilylation; the latter includes double alkylation and epoxidation Mechanistic studies clarified the role of the two Lewis acids: the Zn-pyridine-base complex catalyzes the dehydrogenative silylation as a 1st stage, and, following on this, the In Lewis acid catalyzes the ring-closing hydrosilylation as a 2nd stage, thus leading to the 1,1-disilylalkene.
This compound(Diphenyl-2-pyridylphosphine)Synthetic Route of C17H14NP was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.
Reference:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem