Townley, Chloe; McMurray, Lindsay; Marsden, Stephen P.; Nelson, Adam published the artcile< A unified ""top-down"" approach for the synthesis of diverse lead-like molecular scaffolds>, Computed Properties of 3336-49-0, the main research area is organic mol scaffold diastereoselective preparation; Molecular diversity; Molecular scaffolds; Screening compounds.
A “”top-down”” synthetic approach enabled the step-efficient synthesis of 21 diverse novel mol. scaffolds. The scaffolds were derived from four complex intermediates that had been prepared using cycloaddition chem. Scaffold-hopping of these intermediates was achieved through attachment of an addnl. ring, ring cleavage, ring expansion and/or ring fusion. It was shown that the resulting scaffolds could be decorated to yield diverse lead-like screening compounds
Bioorganic & Medicinal Chemistry Letters published new progress about 1,4-Addition reaction catalysts. 3336-49-0 belongs to class isoquinoline, and the molecular formula is C9H7NO, Computed Properties of 3336-49-0.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem